P: One has to work hard to establish, develop and maintain deep and lasting bonds with those who matter in one’s life. Q: As "Man is not an island entire of itself", he cannot be happy in isolation. R: Humans live out their life in the company of their family, friends, colleagues, superiors, even total strangers in buses and lifts. S: And, brick by brick, they must build their relationship with each one, to lay a secure foundation for their road to happiness.
Here, Q is the introductory statement, hence the first sentence of the passage. R is the second sentence. After stating that people should not be isolated, the importance of having company must be stated. P is the last sentence of the passage and follows S. So, the correct sequence is QRSP.
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