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In the sentence, "Despite his perspicacious observations, his advice was often ignored," the word "perspicacious" means highly perceptive, sharp, or having keen insight. Here are the options provided: 1. Astute – This means shrewd, perceptive, and having keen insight, making it the closest synonym for "perspicacious." (Correct) 2. Vacuous – This means lacking intelligence or thought, which is the opposite of perspicacious. (Incorrect) 3. Dubious – This means doubtful or uncertain, which does not match the meaning of perspicacious. (Incorrect) 4. Trivial – This means insignificant or unimportant, which does not relate to being insightful. (Incorrect) The word that best replaces "perspicacious" without changing the meaning of the sentence is: (1) Astute.
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