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    Question

    What is the significance of the R21/Matrix-M malaria

    vaccine receiving the World Health Organisation's (WHO) recommendation?
    A It's the first COVID-19 vaccine approved for global use Correct Answer Incorrect Answer
    B It's the first malaria vaccine recommended for use by WHO Correct Answer Incorrect Answer
    C It's a vaccine developed by Novavax for a different infectious disease Correct Answer Incorrect Answer
    D It's a vaccine designed for tuberculosis prevention Correct Answer Incorrect Answer
    E It's a vaccine developed for use in non-endemic countries Correct Answer Incorrect Answer

    Solution

    The R21/Matrix-M malaria vaccine developed by the University of Oxford and the Serum Institute of India, leveraging Novavax’s adjuvant technology, has been recommended for use by the World Health Organisation (WHO) after meeting required safety, quality and effectiveness standards Following a detailed scientific review by the WHO’s independent advisory body, the Strategic Advisory Group of Experts (SAGE) and the Malaria Policy Advisory Group (MPAG), the R21/Matrix-M malaria vaccine has been recommended for use, noted a release issued by the Serum Institute of India. With the approval and recommendations by the WHO, additional regulatory approvals are expected to follow shortly and R21/Matrix-M vaccine doses could be ready to begin wider roll-out as early as next year. The Serum Institute has already established production capacity for 100 million doses per annum, which will be doubled over the next two years. This scale of production is critical because vaccinating those at high risk of malaria will be important in stemming the spread of disease, as well as protecting the vaccinated The Matrix-M component is a proprietary saponin-based adjuvant from Novavax, which is licensed to the Serum Institute for use in endemic countries, while Novavax retains commercial rights in non-endemic countries.

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